Factors which are predicative from the point of view of forming intravesicular obstruction after HIFU-ablation in connection with localized prostate carcinoma

R.S. Fomkin, V.M. Popkov, T.V. Shatylko
Keywords: prostate cancer, HIFU, bladder outlet obstruction
Medicinskij al'manah, 2015, issue 2, pages 68-71.

Objective: To assess factors potentially affecting the development of bladder outlet obstruction after highintensity

ultrasound ablation for localized prostate cancer. Methods: In a retrospective analysis included

patients with a follow after HIFU-ablation of 1 year. Results: The mean follow analyzed for 275 patients was

24±1,0 months. Bladder outlet obstruction developed in 79 patients (25,1%), 19 of whom had recurrent

episodes of IVO. Period before the development of bladder outlet obstruction averaged 11,2±1,3 months.

Were cause bladder outlet obstruction Bladder neck sclerosis, prostate necrosis distal urethral stricture

and stenosis of 64 (81%) 24 (30,4%) 13 (16.5%) and 10 (12,7%) cases, respectively. Age at the time of

HIFU-ablation was the only factor that is largely associated with the development of bladder outlet

obstruction (p=0,021). In patients with recurrent bladder outlet obstruction Glan cause it was the bladder

neck sclerosis. The incidence of recurrent obstruction was significantly reduced by increasing the volume

of the resected before HIFU-tissue ablation (p=0,031).

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R.S. Fomkin, V.M. Popkov, T.V. Shatylko Factors which are predicative from the point of view of forming intravesicular obstruction after HIFU-ablation in connection with localized prostate carcinoma. Medicinskij al'manah 2015; (2): 68–71